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One or more keywords matched the following properties of Gaffney, Patrick
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preferred title J.G. Puterbaugh Chair in Medical Research
One or more keywords matched the following items that are connected to Gaffney, Patrick
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Concept Stromal Interaction Molecule 1
Concept ORAI1 Protein
Concept Transcription Factor HES-1
Concept Industrial Development
Concept Ku Autoantigen
Concept RNA Splicing Factors
Concept Tumor Necrosis Factor alpha-Induced Protein 3
Concept Firmicutes
Concept Interferon-Induced Helicase, IFIH1
Concept Gastrointestinal Microbiome
Concept Autophagy-Related Proteins
Concept Adolescent
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Concept Africa
Concept Aneuploidy
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Concept Apolipoprotein L1
Concept Age Factors
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Concept Agriculture
Concept Antibodies, Viral
Concept CCCTC-Binding Factor
Concept Histocompatibility Antigens Class II
Concept Antigens, Neoplasm
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Concept Algorithms
Concept Antibodies, Antinuclear
Concept Alleles
Concept California
Concept Amino Acid Sequence
Concept African Americans
Concept Axons
Concept Carcinoma, Squamous Cell
Concept B-Lymphocytes
Concept Blood Platelet Disorders
Concept Blood Proteins
Concept Blood Specimen Collection
Concept Bone Diseases, Developmental
Concept Carotid Artery Diseases
Concept Carrier Proteins
Concept Base Composition
Concept Base Sequence
Concept Bayes Theorem
Concept Cell Differentiation
Concept Cell Line
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Concept Cell Movement
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Concept Cytoskeleton
Concept Binding Sites
Concept Biological Products
Concept Computer Simulation
Concept Delaware
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Concept Demography
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Concept Chromatin
Concept Chromosome Mapping
Concept Chromosomes, Human, Pair 1
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Concept Contrast Media
Concept Depressive Disorder, Major
Concept Crohn Disease
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Concept Diabetes Mellitus, Type 1
Concept Europe
Concept Exodeoxyribonucleases
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Concept Carcinoma, Adenoid Cystic
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Concept Endoplasmic Reticulum
Concept Family Health
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Concept Enhancer Elements, Genetic
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Concept Drosophila
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Concept Herpesvirus 4, Human
Concept Fibrin
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Concept Herpesviridae Infections
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Concept Head and Neck Neoplasms
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Concept Genetic Markers
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Concept Lupus Vulgaris
Concept Lupus Erythematosus, Cutaneous
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Concept Korea
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Concept Male
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Concept Inflammation
Concept Insulin-Like Growth Factor I
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Concept Muscle Hypotonia
Concept Interferon Type I
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Concept Nicotinamide-Nucleotide Adenylyltransferase
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Concept Minnesota
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Concept Osteosarcoma
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Concept Autoimmunity
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Concept 2',5'-Oligoadenylate Synthetase
Concept 25-Hydroxyvitamin D3 1-alpha-Hydroxylase
Concept Genomic Library
Concept Meta-Analysis as Topic
Concept Reproducibility of Results
Concept Calcium Channels
Concept HLA-B Antigens
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Concept Protozoan Proteins
Concept HLA-DR2 Antigen
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Concept Linkage Disequilibrium
Concept Cell Adhesion Molecules
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Concept Gene Rearrangement
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Concept Molecular Probe Techniques
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Concept Interleukin-10
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Concept Complement Factor H
Concept CD3 Complex
Concept Substrate Specificity
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Concept Endarterectomy, Carotid
Concept Interferon-alpha
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Concept Genetic Variation
Concept Alternative Splicing
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Concept Sequence Analysis, DNA
Concept Protein Structure, Secondary
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Concept Receptors, Complement 3b
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Concept Receptors, Interferon
Concept Protein Tyrosine Phosphatases
Concept Virus Diseases
Concept Cell Cycle Proteins
Concept Intercellular Adhesion Molecule-1
Concept Vitamin D
Concept Vitamin D Deficiency
Concept Vitamin D-Binding Protein
Concept Vitamins
Concept Codon, Initiator
Concept Genes, cdc
Concept Inflammation Mediators
Concept Homeodomain Proteins
Concept Patch-Clamp Techniques
Concept Disease Progression
Concept Muscle, Skeletal
Concept Microsatellite Repeats
Concept Genome, Protozoan
Concept Gene Expression Regulation, Developmental
Concept ATP-Binding Cassette Transporters
Concept Cell Culture Techniques
Concept Risk Assessment
Concept Hyaluronan Receptors
Concept Mutagenesis, Site-Directed
Concept NF-kappa B
Concept Gene Dosage
Concept Interleukin-12
Concept Myosin Heavy Chains
Concept P-Selectin
Concept CD40 Antigens
Concept Founder Effect
Concept Statistics, Nonparametric
Concept src-Family Kinases
Concept Tenascin
Concept Sequence Alignment
Concept Genetic Heterogeneity
Concept Motor Neuron Disease
Concept Muscle Fatigue
Concept Matched-Pair Analysis
Concept Mutation, Missense
Concept Reverse Transcriptase Polymerase Chain Reaction
Concept Catalytic Domain
Concept Proteome
Concept Physical Chromosome Mapping
Concept Polymorphism, Single Nucleotide
Concept Heredodegenerative Disorders, Nervous System
Concept Leptin
Concept Receptors, Interleukin
Concept Phosphatidylinositol Phosphates
Concept Molecular Motor Proteins
Concept Oligonucleotide Array Sequence Analysis
Concept Multifactorial Inheritance
Concept 3' Untranslated Regions
Concept Receptors, Calcitriol
Concept rac1 GTP-Binding Protein
Concept Activin Receptors, Type I
Concept Genetic Diseases, Inborn
Concept Databases, Genetic
Concept beta Karyopherins
Concept Mice, Knockout
Concept Quantitative Trait, Heritable
Concept Drosophila Proteins
Concept Peptidylprolyl Isomerase
Concept Gadolinium DTPA
Concept Zebrafish Proteins
Concept Chondrocytes
Concept Biotinylation
Concept Cyclin D1
Concept Amino Acid Substitution
Concept Mitogen-Activated Protein Kinase 1
Concept Electron Transport Complex I
Concept Proprotein Convertases
Concept Promoter Regions, Genetic
Concept Calcium Signaling
Concept K562 Cells
Concept Genetic Predisposition to Disease
Concept Base Pairing
Concept Protein Isoforms
Concept Glyceraldehyde 3-Phosphate Dehydrogenase (NADP+)
Concept Epigenesis, Genetic
Concept Mitochondrial Proton-Translocating ATPases
Concept Protein Binding
Concept Protein Conformation
Concept Protein Kinase C
Concept Principal Component Analysis
Concept Proto-Oncogene Proteins
Concept American Native Continental Ancestry Group
Concept Psoriasis
Concept Psychiatric Status Rating Scales
Concept Ubiquitin-Conjugating Enzymes
Concept Biodiversity
Concept Basic-Leucine Zipper Transcription Factors
Concept YY1 Transcription Factor
Concept Apoptosis Regulatory Proteins
Concept bcl-X Protein
Concept Sialyltransferases
Concept Proto-Oncogene Proteins c-akt
Concept Sjogren's Syndrome
Concept Skin Diseases
Concept Skin Physiological Phenomena
Concept Toll-Like Receptor 7
Concept Toll-Like Receptor 9
Concept Mice
Concept Rats
Concept Genetic Pleiotropy
Concept Socioeconomic Factors
Concept Software
Concept Proto-Oncogene Proteins c-vav
Concept Spectrin
Concept Mass Spectrometry
Concept Metagenome
Concept Genome-Wide Association Study
Concept Trisomy
Concept Biomarkers, Tumor
Concept Tumor Necrosis Factor-alpha
Concept Vitamin D3 24-Hydroxylase
Concept Bone Morphogenetic Protein 4
Concept Metabolome
Concept United States
Concept Diet, Paleolithic
Concept Molecular Sequence Annotation
Concept High-Throughput Nucleotide Sequencing
Concept Interleukin-6
Concept Interleukin-7
Concept Up-Regulation
Concept Gene Expression
Concept Miosis
Concept Genome, Human
Concept Complement C1q
Concept Gene Expression Regulation, Neoplastic
Concept Antigens, Nuclear
Concept Prevalence
Concept Cluster Analysis
Concept Confidence Intervals
Concept Chi-Square Distribution
Concept Logistic Models
Concept Odds Ratio
Concept Case-Control Studies
Concept Transcriptome
Concept Exome
Concept Telomere Homeostasis
Concept DNA, Protozoan
Concept MicroRNAs
Concept Siblings
Concept Immunophenotyping
Concept Polymerase Chain Reaction
Concept Intercellular Signaling Peptides and Proteins
Concept Genes, Tumor Suppressor
Concept B-Lymphocyte Subsets
Concept HLA-DR beta-Chains
Concept HLA-DRB1 Chains
Concept HLA-DQ alpha-Chains
Concept Endoplasmic Reticulum Stress
Concept HLA-DQ beta-Chains
Concept Matrix Attachment Region Binding Proteins
Concept Lectins, C-Type
Concept Cytokines
Concept Genotyping Techniques
Concept Mutagenesis, Insertional
Concept Genes, myc
Concept Chromatin Immunoprecipitation
Concept Casein Kinase II
Concept Intracellular Signaling Peptides and Proteins
Concept Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
Concept TNF Receptor-Associated Factor 6
Concept JNK Mitogen-Activated Protein Kinases
Concept Self Tolerance
Concept Age of Onset
Concept Datasets as Topic
Concept In Vitro Techniques
Concept Sex Distribution
Concept Adaptor Proteins, Signal Transducing
Concept Cell Proliferation
Concept Nanostructures
Concept CD11b Antigen
Concept Gene Regulatory Networks
Concept OX40 Ligand
Concept Multipotent Stem Cells
Concept Actinobacteria
Concept DEAD-box RNA Helicases
Concept Quantitative Trait Loci
Concept Genetic Load
Concept Proteomics
Concept Limb Deformities, Congenital
Concept Chromosomes, Human, X
Concept Interleukin-1 Receptor-Associated Kinases
Concept Interleukin-2 Receptor alpha Subunit
Concept Bacteroidetes
Concept Chromatin Assembly and Disassembly
Concept DNA Primers
Concept Oral Ulcer
Concept Interleukin-21 Receptor alpha Subunit
Concept Nanoparticles
Concept Proto-Oncogene Proteins c-bcl-2
Concept NADPH Oxidases
Concept Computational Biology
Concept Oleic Acid
Concept Lipogenesis
Concept Republic of Korea
Concept Podocytes
Concept Insect Proteins
Concept Bone Morphogenetic Proteins
Concept Mutant Proteins
Concept Area Under Curve
Concept COS Cells
Concept High-Throughput Screening Assays
Concept Proto-Oncogene Protein c-ets-1
Concept STAT1 Transcription Factor
Concept Sequence Inversion
Concept STAT4 Transcription Factor
Concept ets-Domain Protein Elk-1
Concept Interferon Regulatory Factors
Concept Gene Expression Profiling
Concept Myopathies, Structural, Congenital
Concept Eosinophilic Esophagitis
Concept HEK293 Cells
Concept Epigenomics
Concept Precursor Cell Lymphoblastic Leukemia-Lymphoma
Concept Chemokine CXCL10
Concept Receptors, CCR
Concept Protein Transport
Concept CRISPR-Cas Systems
Concept Protein Tyrosine Phosphatase, Non-Receptor Type 1
Concept Protein Tyrosine Phosphatase, Non-Receptor Type 22
Concept Protein Phosphatase 2
Concept 3-Phosphoinositide-Dependent Protein Kinases
Concept Gene Order
Concept Genomics
Concept Electrophoretic Mobility Shift Assay
Concept Receptors, Purinergic P2Y2
Concept Sex Chromosome Disorders of Sex Development
Concept Cell Line, Tumor
Concept Microarray Analysis
Concept Multiprotein Complexes
Concept Ikaros Transcription Factor
Concept Protein Kinase C-delta
Concept Methyl-CpG-Binding Protein 2
Concept Basic Helix-Loop-Helix Transcription Factors
Concept Hypoxia-Inducible Factor 1
Concept Inhibitor of Differentiation Protein 1
Concept Immunoglobulin J Recombination Signal Sequence-Binding Protein
Concept Gene Knockdown Techniques
Concept Gene Knockout Techniques
Concept Sex-Determining Region Y Protein
Concept Receptors, Notch
Concept Smad1 Protein
Concept Young Adult
Concept Bone Morphogenetic Protein Receptors
Concept Benzodioxoles
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Concept Genetic Loci
Concept Adaptive Immunity
Concept Genetic Association Studies
Concept Fetal Globulins
Concept Real-Time Polymerase Chain Reaction
Concept V-Set Domain-Containing T-Cell Activation Inhibitor 1
Concept Apolipoproteins
Concept Argentina
Concept Arteriosclerosis
Concept Arthritis, Juvenile
Concept Arthritis, Rheumatoid
Concept Asian Americans
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Concept Chile
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Concept DNA
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Concept Ostreidae
Academic Article PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.
Academic Article Genome scan of human systemic lupus erythematosus by regression modeling: evidence of linkage and epistasis at 4p16-15.2.
Academic Article Recent advances in the genetics of systemic lupus erythematosus.
Academic Article Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus.
Academic Article Expression levels for many genes in human peripheral blood cells are highly sensitive to ex vivo incubation.
Academic Article Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.
Academic Article Molecular imaging of human thrombus with computed tomography.
Academic Article Complete mitochondrial DNA sequence of the eastern oyster Crassostrea virginica.
Academic Article Targeted PARACEST nanoparticle contrast agent for the detection of fibrin.
Academic Article Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus.
Academic Article Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus.
Academic Article High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups.
Academic Article Replication of the BANK1 genetic association with systemic lupus erythematosus in a European-derived population.
Academic Article Genetic associations of LYN with systemic lupus erythematosus.
Academic Article Meta-analysis and imputation identifies a 109 kb risk haplotype spanning TNFAIP3 associated with lupus nephritis and hematologic manifestations.
Academic Article Complement receptor 2 polymorphisms associated with systemic lupus erythematosus modulate alternative splicing.
Academic Article Variation in the ATP-binding cassette transporter 2 gene is a separate risk factor for systemic lupus erythematosus within the MHC.
Academic Article Peripheral blood gene expression profiling in Sjögren's syndrome.
Academic Article Variation in the upstream region of P-Selectin (SELP) is a risk factor for SLE.
Academic Article High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.
Academic Article Defining a new molecular basis of systemic lupus erythematosus through transcriptional profiling.
Academic Article Evidence for gene-gene epistatic interactions among susceptibility loci for systemic lupus erythematosus.
Academic Article Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.
Academic Article Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry.
Academic Article An enhancer element harboring variants associated with systemic lupus erythematosus engages the TNFAIP3 promoter to influence A20 expression.
Academic Article Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome.
Academic Article Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression.
Academic Article GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.
Academic Article Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
Academic Article Use of next-generation DNA sequencing to analyze genetic variants in rheumatic disease.
Academic Article Identification of a New Susceptibility Locus for Systemic Lupus Erythematosus on Chromosome 12 in Individuals of European Ancestry.
Academic Article Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus.
Academic Article X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome.
Academic Article Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production.
Academic Article Expression and methylation data from SLE patient and healthy control blood samples subdivided with respect to ARID3a levels.
Academic Article A missense variant in NCF1 is associated with susceptibility to multiple autoimmune diseases.
Academic Article ßIV Spectrinopathies Cause Profound Intellectual Disability, Congenital Hypotonia, and Motor Axonal Neuropathy.
Academic Article From association to mechanism in complex disease genetics: the role of the 3D genome.
Academic Article Association of Epstein-Barr virus serological reactivation with transitioning to systemic lupus erythematosus in at-risk individuals.
Academic Article 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase.
Academic Article Identification of a gene expression signature associated with recurrent disease in squamous cell carcinoma of the head and neck.
Academic Article The use of microarrays to study autoimmunity.
Academic Article Microsatellite marker development and analysis in the eastern oyster (Crassostrea virginica): confirmation of null alleles and non-Mendelian segregation ratios.
Academic Article Gene expression profiling in human autoimmunity.
Academic Article Fine-mapping chromosome 20 in 230 systemic lupus erythematosus sib pair and multiplex families: evidence for genetic epistasis with chromosome 16q12.
Academic Article Endogenous heparan sulfate and heparin modulate bone morphogenetic protein-4 signaling and activity.
Academic Article Identification of new SLE-associated genes with a two-step Bayesian study design.
Academic Article Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study.
Academic Article Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups.
Academic Article The rs4774 CIITA missense variant is associated with risk of systemic lupus erythematosus.
Academic Article Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility.
Academic Article Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK.
Academic Article The genomics of autoimmune disease in the era of genome-wide association studies and beyond.
Academic Article Contributions of mass spectrometry-based proteomics to defining cellular mechanisms and diagnostic markers for systemic lupus erythematosus.
Academic Article Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus.
Academic Article RBPJ mutations identified in two families affected by Adams-Oliver syndrome.
Academic Article Impact of genetic ancestry and sociodemographic status on the clinical expression of systemic lupus erythematosus in American Indian-European populations.
Academic Article Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups.
Academic Article WITHDRAWN: A female autoimmunity gene exists: DDX3X.
Academic Article Protein kinase cd deficiency causes mendelian systemic lupus erythematosus with B cell-defective apoptosis and hyperproliferation.
Academic Article Encore: Genetic Association Interaction Network centrality pipeline and application to SLE exome data.
Academic Article Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations.
Academic Article Activating mutations in STIM1 and ORAI1 cause overlapping syndromes of tubular myopathy and congenital miosis.
Academic Article MHC associations with clinical and autoantibody manifestations in European SLE.
Academic Article Forward genetic screening identifies a small molecule that blocks Toxoplasma gondii growth by inhibiting both host- and parasite-encoded kinases.
Academic Article Subsistence strategies in traditional societies distinguish gut microbiomes.
Academic Article A20-Binding Inhibitor of NF-?B Activation 1 is a Physiologic Inhibitor of NF-?B: A Molecular Switch for Inflammation and Autoimmunity.
Academic Article TALEN-mediated enhancer knockout influences TNFAIP3 gene expression and mimics a molecular phenotype associated with systemic lupus erythematosus.
Academic Article Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity.
Academic Article Combined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus.
Academic Article Association of IFIH1 and pro-inflammatory mediators: Potential new clues in SLE-associated pathogenesis.
Academic Article Polygenic risk assessment reveals pleiotropy between sarcoidosis and inflammatory disorders in the context of genetic ancestry.
Academic Article Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons.
Academic Article Association of Natural Killer Cell Ligand Polymorphism HLA-C Asn80Lys With the Development of Anti-SSA/Ro-Associated Congenital Heart Block.
Academic Article Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis.
Academic Article A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus.
Academic Article Genome screening in human systemic lupus erythematosus: results from a second Minnesota cohort and combined analyses of 187 sib-pair families.
Academic Article Genetic linkage and transmission disequilibrium of marker haplotypes at chromosome 1q41 in human systemic lupus erythematosus.
Academic Article Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus.
Academic Article Improved molecular imaging contrast agent for detection of human thrombus.
Academic Article Genes associated with early development, apoptosis and cell cycle regulation define a gene expression profile of adenoid cystic carcinoma.
Academic Article Familial aggregation and linkage analysis of autoantibody traits in pedigrees multiplex for systemic lupus erythematosus.
Academic Article A novel polymorphism of the human CD40 receptor with enhanced function.
Academic Article Evaluation of imputation-based association in and around the integrin-alpha-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE).
Academic Article Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.
Academic Article A polymorphism within IL21R confers risk for systemic lupus erythematosus.
Academic Article European population substructure is associated with mucocutaneous manifestations and autoantibody production in systemic lupus erythematosus.
Academic Article Analysis of maternal-offspring HLA compatibility, parent-of-origin effects, and noninherited maternal antigen effects for HLA-DRB1 in systemic lupus erythematosus.
Academic Article Exon 6 variants carried on systemic lupus erythematosus (SLE) risk haplotypes modulate IRF5 function.
Academic Article The role of genetic variation near interferon-kappa in systemic lupus erythematosus.
Academic Article Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort.
Academic Article Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus.
Academic Article IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus.
Academic Article Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus.
Academic Article Sex chromosome aneuploidies among men with systemic lupus erythematosus.
Academic Article Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study.
Academic Article Identification of novel coding mutation in C1qA gene in an African-American pedigree with lupus and C1q deficiency.
Academic Article A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus.
Academic Article Effects of IRF5 lupus risk haplotype on pathways predicted to influence B cell functions.
Academic Article Variation in the ICAM1-ICAM4-ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries.
Academic Article Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production.
Academic Article Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4.
Academic Article Infinium assay for large-scale SNP genotyping applications.
Academic Article Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription.
Academic Article Disease mechanisms in rheumatology--tools and pathways: defining functional genetic variants in autoimmune diseases.
Academic Article Genetic association of CD247 (CD3?) with SLE in a large-scale multiethnic study.
Academic Article Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression.
Academic Article Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.
Academic Article Transancestral mapping and genetic load in systemic lupus erythematosus.
Academic Article Site-1 protease deficiency causes human skeletal dysplasia due to defective inter-organelle protein trafficking.
Academic Article Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks.
Academic Article Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans.
Academic Article Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients.
Academic Article Role of Systemic Lupus Erythematosus Risk Variants With Opposing Functional Effects as a Driver of Hypomorphic Expression of TNIP1 and Other Genes Within a Three-Dimensional Chromatin Network.
Academic Article A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families.
Academic Article The genetics of human systemic lupus erythematosus.
Academic Article PARP alleles and SLE: failure to confirm association with disease susceptibility.
Academic Article Fatal acute lymphoblastic leukemia in mice transgenic for B cell-restricted bcl-xL and c-myc.
Academic Article Keys to unlocking the mysteries of rheumatic autoimmune disease.
Academic Article Fine mapping chromosome 16q12 in a collection of 231 systemic lupus erythematosus sibpair and multiplex families.
Academic Article Quantitative "magnetic resonance immunohistochemistry" with ligand-targeted (19)F nanoparticles.
Academic Article Progress towards understanding the genetic pathogenesis of systemic lupus erythematosus.
Academic Article Meta-analysis of genome-wide linkage studies of systemic lupus erythematosus.
Academic Article Specific combinations of HLA-DR2 and DR3 class II haplotypes contribute graded risk for disease susceptibility and autoantibodies in human SLE.
Academic Article Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.
Academic Article Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus.
Academic Article Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
Academic Article Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus.
Academic Article Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes.
Academic Article Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.
Academic Article Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21.
Academic Article Genetic analyses of interferon pathway-related genes reveal multiple new loci associated with systemic lupus erythematosus.
Academic Article Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study.
Academic Article A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap.
Academic Article Role of MYH9 and APOL1 in African and non-African populations with lupus nephritis.
Academic Article Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase.
Academic Article Evaluation of TRAF6 in a large multiancestral lupus cohort.
Academic Article Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans.
Academic Article MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus.
Academic Article PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes.
Academic Article ABIN1 dysfunction as a genetic basis for lupus nephritis.
Academic Article Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA.
Academic Article The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.
Academic Article Lupus risk variants in the PXK locus alter B-cell receptor internalization.
Academic Article Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.
Academic Article Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.
Academic Article Gut Microbiome Diversity among Cheyenne and Arapaho Individuals from Western Oklahoma.
Academic Article Human effector B lymphocytes express ARID3a and secrete interferon alpha.
Academic Article Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly.
Academic Article Lupus-related single nucleotide polymorphisms and risk of diffuse large B-cell lymphoma.
Academic Article Identification and replication of RNA-Seq gene network modules associated with depression severity.
Academic Article Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31.
Academic Article Nearest-Neighbor Projected Distance Regression for Epistasis Detection in GWAS With Population Structure Correction.
Academic Article Correction: Identification and replication of RNA-Seq gene network modules associated with depression severity.
Academic Article Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus.
Academic Article Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly.
Grant Candidate Causal Variants in Systemic Lupus Erythematosus
Grant Epigenome-Guided Causal Variant Discovery and Mechanisms
Grant TNFAIP3 (A20) and Susceptibility to Systemic Lupus Erythematosus
Grant Comprehensive Candidate Pathway Analysis in SLE
Grant Molecular Mechanisms and Genetics of Autoimmunity
Grant Functional Mechanisms of Causal Variants in Systemic Lupus Erythematosus
Grant Comprehensive Candidate Pathway Analysis in SLE
Grant Genetic and functional studies of the CD40 P227A polymorphism
Grant Molecular Mechanisms and Genetics of Autoimmunity COBRE
Grant ISOLATION OF A HUMAN SLE SUSCEPTIBILITY GENE ON CHROMOSO
Grant Molecular Mechanisms and Genetics of Autoimmunity
Academic Article CD4+?T cells from children with active juvenile idiopathic arthritis show altered chromatin features associated with transcriptional abnormalities.
Academic Article Chromatin Looping Links Target Genes with Genetic Risk Loci for Dermatological Traits.
Grant Disease and Race Specific Single-cell Epigenetic Mechanisms in Human SLE
Academic Article Variants on the UBE2L3/YDJC Autoimmune Disease Risk Haplotype Increase UBE2L3 Expression by Modulating CCCTC-Binding Factor and YY1 Binding.
Academic Article Deficiencies in the DNA Binding Protein ARID3a Alter Chromatin Structures Important for Early Human Erythropoiesis.
Academic Article Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells.
Academic Article A Human MSH6 Germline Variant Associated With Systemic Lupus Erythematosus Induces Lupus-like Disease in Mice.
Academic Article Relationship Between a Vitamin D Genetic Risk Score and Autoantibodies Among First-Degree Relatives of Probands With Rheumatoid Arthritis and Systemic Lupus Erythematosus.
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